The porphyria therapies market is projected to grow at an annualized rate of 10.97% during the period 2021-2030, claims Roots Analysis

Roots Analysis has announced the addition of “Porphyria Targeting Therapies Market, 2021-2030” report to its list of offerings. rnrnPorphyria is a rare disorder that is characterized by excessive accumulation of porphyrin, a compound that aids in the formation of heme (an essential part of hemoglobin that helps carry oxygen in blood). Any anomaly caused by genetic or acquired abnormalities in heme biosynthesis (produced majorly in bone marrow and liver) can result in toxicity. It is worth highlighting that, till date, more than 1,000 mutations that can cause porphyria have been identified. However, prevalence of porphyria still remains unknown. Several treatment options such as gene therapy, proteasome inhibition and pharmacologic chaperones are currently being investigated among various other targeted treatment options.rnrnTo order this 130+ slides report, which features 90+ figures, please visit https://www.rootsanalysis.com/reports/porphyria-pipline-review.html.rnrnKey Market Insights rnrn15+ therapies have been / are being developed for the treatment of different types of porphyriarnMore than 70% of the aforementioned candidates are currently under clinical evaluation. Further, three therapies, namely Panhematin™, GIVLAARI® and SCENESSE®, have already been approved for the treatment of different types of porphyria.rnrnAround 50% of the therapeutics are being developed as biologicsrnMajority (over 65%) of the abovementioned biologic drugs have been / are being designed for administration via the intravenous route. Furthermore, majority of the drugs (37%) have been / are being targeting acute intermittent porphyria.rnrnOver 30% of the therapies have been / are being developed for erythropoietic protoporphyria rnMore than 65% the abovementioned therapies are currently being evaluated in clinical phases. Further, around 60% of the aforementioned therapy candidates are being developed as small molecules.rnrnMore than 45% of the players evaluating therapies for porphyria are small companiesrnNorth America has emerged as a key hub for the development of porphyria therapies, featuring the presence of 65% developers. The developer landscape is further dominated by players that have been established between 2001-2010, representing around 45% of the total number of stakeholders.rnrnA number of clinical trials evaluating therapies for porphyria, have been registeredrnMajority of the clinical studies have been completed. More than 30% of the overall trials are phase I studies. Further, it is worth noting that, most of the trials (~ 60%) focused on porphyria therapies were registered post-2010.rnrnPartnership activity in this field has increased at a CAGR of 9.6%, between 2018 and 2020rnMore than 70% of the reported deals were established post-2018, with the maximum activity being reported in 2019 and 2020. Majority of the instances captured in the report were product distribution / commercialization agreements (~45%). rnrn380+ articles have been published related to porphyria, since January 2018rnClose to 20% publications mentioned in the report were focused on the assessment of therapeutics that have been / are being developed for the treatment of erythropoietic protoporphyria. Example of prominent journals include (in decreasing order of number of publications) Molecular Genetics, Orphanet Journal of Rare Diseases, British Journal of Dermatology and Molecular Genetics, and Metabolism Reports.rnrnAround 15 eminent individuals were identified as key opinion leaders (KOLs) in this domainrnMore than 65% of these KOLs were observed to be associated with organizations based in US, followed by those affiliated to institutes in Spain (20%) and South Africa (7%). Further, over 65% of the KOLs are currently affiliated to academic institutes, such as schools and universities. rnrnNorth America is anticipated to capture over 60% of the global market share in 2030rnIn 2030, more than 50% of the market revenues are expected to be generated from sales of therapeutics intended for the treatment of erythropoietic protoporphyria and porphyria cutanea tarda. Further, therapies designed for oral route of administration are expected to occupy a larger share (51%) of the overall market, in the foreseen future. rnrnTo request a sample copy / brochure of this report, please visit this https://www.rootsanalysis.com/reports/porphyria-pipline-review/request-sample.htmlrnrnKey Questions Answeredrn What are the prevalent R&D trends related to Porphyria?rn What are the key challenges faced by stakeholders engaged in this domain?rn What are the principal therapies developed by the companies in this domain?rn Who are the leading industry and non-industry players in this market?rn What are the key geographies where research on porphyria is actively being conducted?rn Who are the key investors in this domain? rn Who are the key opinion leaders / experts in this field?rn What kind of partnership models are commonly adopted by industry stakeholders? rn What are the factors that are likely to influence the evolution of this upcoming market?rn How is the current and future market opportunity likely to be distributed across key market segments?rnrnThe financial opportunity within the porphyria therapies market has been analyzed across the following segments:rnrn Drug rn GIVLAARI®rn Panhematin®rn SCENESSE®rn MT-7117rn Colestidrn HARVONI®rnrn Type of Porphyriarn Acute Hepatic Porphyriarn Acute Intermittent Porphyriarn Erythropoietic Protoporphyriarn Hereditary Coproporphyriarn Porphyria Cutanea Tardarn Variegate Porphyriarn X-Linked Porphyriarnrn Route of Administrationrn Oralrn Intravenousrn Subcutaneousrnrn Key Geographical Regionsrn North Americarn Europern Asia-PacificrnrnThe research includes profiles of key players (listed below); each profile features a brief overview of company, pipeline details, recent developments (including collaborations and expansions) and an informed future outlook.rn Agios Pharmaceuticalrn Alnylam Pharmaceuticalsrn Clinuvel Pharmaceuticals rn Disc Medicine rn Mitsubishi Tanabe Pharma rn Moderna Therapeuticsrn Palatin Technologies rn Recordati Rare DiseasesrnrnFor additional details, please visit https://www.rootsanalysis.com/reports/porphyria-pipline-review.html or email [email protected] rnrnYou may also be interested in the following titles: rn1. Progressive Supranuclear Palsy: Pipeline Review, Developer Landscape and Competitive Insights, 2021-2030rn2. Soft Tissue Sarcoma: Pipeline Review, Developer Landscape and Competitive Insights, 2021-2030rn3. Polycystic Ovarian Syndrome (PCOS): Pipeline Review, Developer Landscape and Competitive Insights, 2021-2030rnrnContact:rnBen Johnsonrn+1 (415) 800 3415rn+44 (122) 391 [email protected] rnrn https://www.rootsanalysis.com/reports/porphyria-pipline-review.html

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